Common Nausea, Vomiting, Headache, Dizziness, Constipation, Weakness.

Expert advice for Rolazin Tablet
Rolazin prevents new attacks of angina but does not stop an acute attack. Does not affect heart rate, blood pressure at rest or during exercise. Improves HbA1c and blood sugar levels in diabetes patients. Avoid driving or using machinery if you feel dizzy after taking Rolazin. May produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done 1 to 2 weeks after starting Rolazin. Notify your doctor if you are taking any other medications along with Rolazin

Q. What is Rolazin extended-release(ER) tablet?
Rolazin extended release (ER) means the pill is formulated in such a manner that the drug is released slowly over time and blood levels of a drug are more consistent. This has the advantage of taking fewer pills and also with a lesser gastrointestinal side effect.

Q. Do Rolazin and trimetazidine act in the same way?
No. Both Rolazin and trimetazidine are used for the treatment of angina but they work by a different mechanism. Rolazin works by blocking late sodium current channel during ischemia and thereby lessens the intracellular sodium and calcium overload. This relaxes heart muscles and decreases the oxygen requirement. This helps to prevent angina. Trimetazidine works by improves glucose utilisation of heart cells through inhibition of fatty acid metabolism.

Q. What is the effect of Rolazin in patients with coronary artery disease?
The researcher has studied Rolazin in patients with non-ST-elevation coronary artery disease. It did not reduce the risk of death or recurrent heart attacks in patients, but it improves angina symptoms. It is approved for use in angina.

Q. Can I use rivaroxaban with Rolazin?
Yes. Combining these medications can increase the blood levels of rivaroxaban and increase the risk of serious bleeding complications. You may need a dose adjustment. If you have kidney disease, you should inform your doctor before using rivaroxaban together with Rolazin.

Q. Can I take Rolazin for type 2 diabetes?
No. Rolazin is not approved for treatment of type 2 diabetes. Study have demonstrated its ability to decrease HbA1c (glycosylated haemoglobin) in patients with or without diabetes. This property may be useful in the treatment of patients having diabetes mellitus and angina.

Q. Can I take Rolazin with quetiapine?
No. Using Quetiapine with Ranolazine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.

Q. Is Rolazin good for the heart?
Rolazin is used in a disease of the heart known as angina. It has been shown to improve exercise-induced chest pain and severity of angina.

Q. Are any alternatives to Rolazin?
Yes, there are alternative to Rolazin e.g.Ivabradine, nicorandil and trimetazidine for effective control of anginal symptoms.

Q. Can I take Rolazin with atorvastatin?
Yes. Rolazin may significantly increase the blood levels of atorvastatin. This can increase the risk of side effects such as liver damage and the breakdown of skeletal muscle tissue. It can be used with atorvastatin but with dose limitation (atorvastatin) and appropriate clinical monitoring. In some cases, this can cause kidney damage and even death.

Q. Can I use Rolazin for the treatment of atrial fibrillation?
No. Rolazin is not approved for treatment of atrial fibrillation (AF). The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.

Q. Is Rolazin a beta blocker?
No, Rolazin is not a beta blocker. It is used in the treatment of angina.

Q. Can I take Rolazin with haloperidol?
No. Rolazin should not be used with haloperidol. It may increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.

Q. Is Rolazin effective in arrhythmia?
No. Rolazin is not approved for use in any of arrhythmia. The researcher has demonstrated, its usefulness in patients with Atrial Fibrillation(AF) and in nonsustained ventricular tachycardia (VT) in the experimental model.

Q. What are the contraindications to Rolazin?
Rolazin is contraindicated in patients with liver damage (cirrhosis). It should not be given with medicine like ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, saquinavir, carbamazepine, phenobarbital, phenytoin, rifampin.

Q. Can I use Rolazin for the treatment of diastolic heart failure?
No. Rolazin is not used in the treatment of diastolic heart failure. It is used in the treatment of angina.